Garlic has been recommended by many ancient therapies, including Chinese and Indian medicine, to treat respiratory and digestive problems, as well as microbial infestation and leprosy. The therapeutic effects include numerous benefits for the cardiovascular system, antimicrobial, anticancer, anti-inflammatory, and hormone-like properties. A narrative review was undertaken through the literature in connection to studies published up to the beginning of 2021 on the effect of garlic on staphylococcus aureus bacteria. Garlic aqueous extract is antimicrobial against S. aureus, which is found in hamburger. Furthermore, garlic aqueous extract can be used as a natural addition for hamburger as well as a flavor. Garlic is also antimicrobial against Gram-positive and Gram-negative bacteria.