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EFEITOS HIPOGLICEMIANTE DA PEDRA-UME-CAÁ (MYRCIA MULTIFLORA)

Authors: Klismeny De Souza Bertoldo; Cardoso, Kellen Clicia Alencar; Alves, Andreia Rodrigues; De Oliveira Freitas, Francisca Marta Nascimento; De Sales Ferreirat, José Carlos;

EFEITOS HIPOGLICEMIANTE DA PEDRA-UME-CAÁ (MYRCIA MULTIFLORA)

Abstract

Muitas plantas são usadas para combater o diabetes, pois esta é forma de tratamento mais acessível para diversas classes sociais. O gênero Myrcia possível diversas espécies que são chamadas pedra-ume-caá ou insulina vegetal. Esta revisão tem como objetivo traçar o estado da arte dos estudos fitoquímicos das espécies de Myrcia. Dentre os resultados mais expressivos encontrados, M. multiflora apresentou forte atividade antioxidante pelo método do DPPH do extrato etanólico dos frutos. Diminuição dos níveis de colesterol, triglicerídeose lípase, quando comparados com o padrão lovastanina e orlistat, provavelmente por bloquear a absorção de triglicerídeos devido a um efeito inibitório sobre a lípase em ratos. Inibição da enzima -glucosidase e glicação in vitro, atividade antioxidante, contra os radicais DPPH e ABTS da infusão das folhas. O extrato aquoso de M. sylvatica apresentou potencial anti-inflamatório administrado tanto por via oral quanto por via tópica. M. bella apresentou atividade antioxidante, antimutagênico, citotóxico para linhagens tumorais e de proteção gástrica para o extrato hidrometanólico. O extrato também age na redução glicêmica pós prandial através da inibição da α-glicosidase e α- amilase, ajudando, portanto, na diminuição glicêmica e do quadro diabético. Os resultados mostram que espécies do gênero Myrcia revelou um interessante potencial como hipoglicemiante e antioxidante no tratamento do Diabetes mellitus, além de apresentar ausência de toxicidade, mostrando- se uma alternativa terapêutica efetiva como tratamento adjuvante no controle do Diabetes mellitus.

Keyword: Myrcia, diabetes, antilipidemic, hypoglycemic

Keywords

Myrcia, diabetes, antilipidemica, hipoglicemica.

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selected citations
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This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
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popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
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influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
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impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
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