This report provides a unique, comprehensive and carefully tested methodology for the ethical analysis of emerging technologies, a methodology that is motivated by our earlier studies in the SIENNA project. Our methodology contains seven key steps, the first four of which are directed at defining subject of analysis, aim and scope, and engaging in conceptual analysis and description, and the final three of which specify the actual ethical analysis, with both descriptive and normative components. We provide a detailed account of each of these seven steps and illustrate the application of our methodology to different emerging technologies. Our methodology makes use of methods of foresight analysis and social and environmental impact assessment (SIA), and of stakeholder engagement, and methods for these processes are described in additional sections of the report. We conclude the report by situating our approach within the broader landscape of approaches for technology assessment and impact assessment.