Chronic Kidney disease (CKD) is defined as abnormalities of kidney structure or function which present more than 3 months and implicates general health. Chronic kidney disease (CKD) is one of the serious problems modern medicines, as it’s prevalence and CKD-related problems increasing worldwide. CKD worldwide is 13.4%; According to the statistics,13,4 % of world population suffer from CKD. Approximately 15% of US adults (more than 1 in 7) have CKD. More than 1.2 million people die due to terminal stage of CKD per year in the world. In the Republic of Uzbekistan, the prevalence of terminal CKD was 97.6 per 1 million population (3,210 patients), 2,753 patients (85.8%) were on hemodialysis (HD), and 457 patients (14.2%) had functioning kidney transplant. Kidney pathology occupies an important place among chronic non-infectious diseases due to its significant prevalence, a sharp decrease in the quality of life, high mortality and expensive replacement therapy methods in the terminal stage - dialysis and kidney transplantation. In this regard, it is of interest to study the quality of life (physical condition and psychological health) in patients with CKD receiving program hemodialysis.