Today, organizations need to coordinate their knowledge in order to realize their objectives. The most valuable capital in every organization is its knowledge. In the developed organizations, guiding the valuable thoughts, hidden for the personnel, is done by the propagation of the organizational culture to reach the joint objectives. On the other hand, the information technology (IT) in today’s world overshadows all the domains and our lifestyle. The life of the organizational knowledge depends on the partnership of all staff members and the optimal use of the technology is of high importance to possess this valuable source. As the investment in the sector of the communication and information technology is one of the conditions for possessing this organizational knowledge, functional studies should be conducted in this arena. Therefore, the present research aims at “examining the relationship between the information technology and methods of supporting it in the process of management of science” in the Drug Control Headquarters (DCHQ) of the Presidency and the research is conducted in the second semester of 2012. In this research, a statistical analysis was carried out based on the data collected from a sample made up of some 550 persons of the directors, deputies and heals of different sections of the DCHQ, selected according to a random sampling system. Questionnaires were prepared and distributed among experts through the automated system of the organization and most questionnaires were