The article presents modern ideas about an integrated approach to the treatment and rehabilitation of coronary heart disease (CHD). The main principles of the treatment of chronic coronary artery disease are given, considerable attention is paid to antithrombotic and lipid-lowering therapy, assessment of myocardial viability and management of patients after coronary artery stenting. The practical aspects of the use of antithrombotic and lipid-lowering therapy in patients with stable coronary artery disease are highlighted. The results of our own research are presented. Thus, an individualized approach to the treatment of patients with coronary artery disease who underwent stenting increases the safety and effectiveness of drug treatment and rehabilitation. Achieving and maintaining target levels of platelet and lipid aggregation throughout the entire observation period can significantly reduce the risk of negative cardiac events after SCA.