Abstract: Snake bite envenomation is a global problem affecting mostly the rural communities living in the tropics, where basic health facilities are poor. This cross sectional prospective study was set out to evaluate the effects of envenomation and antivenom on some haematological and haemostatic parameters among patients with snakebite envenomation. In this study total of 286 participants were recruited comprising of 143 patients with snake bite who were treated with Anti-snake-Venom and 143 apparently healthy subjects as control. Blood samples were collected from all the participants and their Haematological parameters evaluated using sysmex KX-21N. The result showed reduced packed cell volume (PCV%) , platelets (Plts 10 ) and haemoglobin concentration (Hb) values of the study group on admission, when compared with the control (p<0.05). While the aPTT and PT levels of the study group were statistically signifcantly higher when compared with their control counterpart (p<0.05). The age, PDW, MPV, TWBC, RBC, Neutrophil, Lymphocyte, and mixed though differ between the control and study group but not statistically significant (p>0.05). The age group that was maximally affected by Snakebite was 18-30 years (55.9%) and the least affected were 0-10 years (3%) and 40 - 70 years (10%). Males had higher incidence (57.4%) as compared to females (42.6%). Farming and cattle rearing were the occupations with high snakebite incidence. In conclusion, PCV, Plt, HB concentration, aPTT and PT were affected significantly by envenomation. However, upon treatment with Anti-Snake-Venom (ASV) within 24 hours there were no significant increase on PDW, MPV RBC, TWBC, differrential (Neut, Lymph) and Mixed. Keywords: global problem, haematological, haemostatic parameters. Title: SOME HAEMOSTATIC AND HAEMATOLOGICAL PARAMETERS OF PATIENTS WITH SNAKEBITE ENVENOMATION BEFORE, DURING AND AFTER TREATMENT IN KALTUNGO GENERAL HOSPITAL, GOMBE STATE, NIGERIA Author: Anyanwu, R.A, Mohammed N.G, Uhunmwangho, E.J, Lele, K.C, Ishaku, S.B International Journal of Healthcare Sciences ISSN 2348-5728 (Online) Vol. 10, Issue 2, October 2022 - March 2023 Page No: 7-13 Research Publish Journals Website: www.researchpublish.com Published Date: 03-October-2022 DOI: https://doi.org/10.5281/zenodo.7139259 Paper Download Link (Source) https://www.researchpublish.com/papers/some-haemostatic-and-haematological-parameters-of-patients-with-snakebite-envenomation-before-during-and-after-treatment-in-kaltungo-general-hospital-gombe-state-nigeria

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International Journal of Healthcare Sciences, ISSN 2348-5728 (Online), Research Publish Journals, Website: www.researchpublish.com