Background: It's intriguing to learn about the various ways traditional plants can be used to treat medical issues. Many studies are being undertaken to see how traditional herbal fruits can help with a variety of medical conditions, including immunodeficiency syndrome. Methods: We employed network pharmacology to discover a biological link between the pharmacological effects of myrolan wood or Haritaki or Terminalia chebula, a traditional Asian medicinal fruit, and HIV pathogenesis in this study. Results: The scientists discovered the common pathway by blocking reverse transcriptase using interrelationship analysis. Conclusion: Terminalia chebula as an HIV treatment could be beneficial. More investigation into the usefulness of myrolan wood fruit in the treatment of HIV is recommended.