The CovidVu study is a national probability survey that collected data on SARS-CoV-2 infection in the U.S. in three rounds: August-December 2020, March-April 2021, and July-September 2021. The goal of this study was to estimate cumulative incidence of SARS-CoV-2 infection in the United States. Surveys were mailed to randomly sampled households in the U.S., and one adult member of the household filled out the questionnaire and sent back SARS-CoV-2 specimens for testing. The data collected included information on social contacts by age, location, and whether they were physical or nonphysical contacts, as well as key demographic information on participants. Survey weights were used to determine unbiased estimates of key parameters, and were based on the population of noninstitutionalized, housed adults (>=18 years of age) in the U.S. Weights were calculated with respect to gender, age, race/ethnicity, education, income, marital status, and census division. For more in-depth information, please visit https://prismhealth.emory.edu/covidvu/ to view recent publications using this data.