Lord Shri Krishna says in Bhagavad Gita Chapter 13, Verse 17: 'I can be attained through Knowledge.' Human birth is the biggest gift to the soul as human beings can realize The Higher Knowledge-The Metaphysical Knowledge. Certainly, lower Knowledge- Physical Knowledge is also crucial to ensure protection and sustenance of human life. Triumph of human life is in realizing the Higher Knowledge with the help of lower Knowledge as an instrument. It is said in Mundaka Upanishad, Verse 1.1.4: There are two sorts of knowledge to be acquired. Those who have realized the Brahman (The Super Power) say Para and Apara, i.e., the Higher and the lower knowledge both the types of knowledge are to be gained and be enriched with. Here lies the importance of Transdisciplinary Teaching-Learning. This research study aims at understanding the Inevitability and Implications of Transdisciplinary Teaching-Learning that covers both the knowledge: the Higher and the lower by studying teachings from The Upanishad and The Bhagavad Gita.