ABSTRACT: In the age of global warming, pandemics and political East-West tensions, the time for science diplomacy has come. Science diplomacy originated during the Cold War era when institutions, such as the International Institute for Applied Systems Analysis (IIASA), built institutional foundations to connect scientists via empirical and rational facts in order to solve global issues of concern aside from potential political realities and country stance differences. Today’s most pressing international challenges in climate change, pandemic prevention and resilient finance despite rising East-West tensions call for a renewed spirit to discuss global problems without political biases and historic international customary practice. KEYWORDS: Climate change, Cultural diplomacy, Global common goods, Global warming, Negotiation, Negotiation Leadership, Pandemic, Prevention, Public policy, Resilience finance, Science diplomacy