Acne vulgaris is a condition where it is characterized by Microcomedones, the earliest lesions of acne, appear at adrenarche, when androgens of adrenal origin begin to stimulate follicular hyperkeratosis and sebaceous hyperplasia in pilosebaceous units on the face.1Mud is one of the rarely used natural modes of treatment in any of the cases. But Black Mud is very useful in conditions of skin ailments.Lodhradilepa has anti-inflammatory action.Therefore, the study was planned to observe the comparative effect of mrittikalepa and lodhradilepa in the management of Acne vulgaris. In the study 30 patients were selected according the classical signs and symptoms of Yuvanapidika& divided into two equal groups comprising of 15 patients in each group. In Group A, 4 patients (26.67%) got mild relief, 3 patients (20%) got moderate relief and 8 patients (53.33%) got marked relief. In Group B, 4 patients (26.67%) got mild relief, 6 patients (40%) got moderate relief and 5 patients (33.33%) got marked relief.Black Mud easily combines with water, absorbs all the seven colours of skin and does not have any adverse effects. It gives cooling effect to the body, because of its moisture retention capacity and it increases the blood circulation and energizes the various skin tissues.2The drug Lodhra, Vachaand Dhanyakaare Kushtagna, Vranaropaka,Vedanasthapaka,Shotahara3might have resulted in good relief.