Background: Direct Laryngoscopy and intubation lead to stress response and sympathetic stimulation which is disadvantage for some high risk patients of cardiac ischemia, raised intracranial tension, cerebral aneurysm, open globe injury, glaucoma etc. Hence reduction of the intense stress response is of utmost importance for a stable and safe hemodynamics in those patients. Aims and Objectives: To access hemodynamic response to laryngoscopy done by the Macintosh/ McCoy blade. Materials and Methods: In this study we had selected 60(male and female in equal number) ASA grade-I&ll patients posted for elective general surgery. They were randomly divided into two groups - group I(laryngoscopy done by Macintosh blade)and group II(laryngoscopy done by McCoy blade). Systolic Blood Pressure, Diastolic Blood Pressure , Mean Blood Pressure and Heart Rate were recorded before and after anaesthesia induction, just after intubation and one, three ,five minutes after orotracheal intubation. Results: The results were compared over time between the two groups. Mean values of Systolic Blood Pressure, Diastolic Blood Pressure, Mean Blood Pressure and heart rate were significantly higher in group 2 as compared to group 1. Conclusion: The stress response was significantly higher when laryngoscopy was done with Macintosh blade as compared with McCoy blade. Intubation with McCoy laryngoscope blade provide better laryngoscopy view.we recommend usage of McCoy blade in routine Anaesthesia practice as non pharmacology means to attenuate haemodynamic response to laryngoscopy& intubation.