Welcome to the 27th NSC Newsletter. As always, we’d like to thank everyone who contributed to this issue. Your input has been HUGELY appreciated. The list of CONTENTS can be found on the next page. Our NSC Coordination Team—Éva Valsami-Jones, Flemming Cassee, and Andreas Falk—are not quite back from holidays , and so business will resume with a CT update in the next NSC Newsletter. Meanwhile, we hope you’ve been able to enjoy getting out and about and seeing colleagues after so many months of on-and-off lockdowns and constraints. Numerous participants attending project events in person as opposed to virtually have valued these opportunities, and the difference in the quality of engagement and interaction has been remarked on by many of us. The benefits of face-to-face meetings were particularly evident during NanoWeek 2022, which is highlighted in the first half of this issue. From the 20th to 24th June, members of the NSC community and colleagues came together in Limassol, Cyprus, for what was to be a highly engaging and enjoyable event. The week was led by NanoCommons in tandem with the organisation of its final conference against the backdrop of sun, sea, sand and science. Travellers to Limassol faced the challenges presented by travel chaos, delayed flights, missed connections, and luggage going on holiday to other distant parts; but all of this was soon forgotten as people came across familiar faces, met old and new colleagues, discovered that people look exactly the same as or indeed completely different from how they appear on Zoom, and then immersed themselves in a stimulating, varied and dynamic programme. The experiences of different NSC projects are accompanied by images of sessions and social events in our special NanoWeek 2022 feature. Following this, we present the reports and updates from a wide range of NSC projects showcasing their recent developments and project outputs. In other news, our newsletter reports from SweNanoSafe and Iriss in Sweden, before introducing the Cefic-LRI Microplastics Cluster of projects. Then follows a not-to-be-missed publications section with news of papers from our projects; details of an opportunity to publish in a special issue of Nanomaterials, titled “Towards a Safe Nanotechnology: Understanding and Controlling Immunomodulatory and Toxicological Properties of Nanomaterials”; further papers of interest; and details of a newly published ISO. Are you thinking about a change? Have a look at the latest job opportunities at CSIC and INL in Spain. Finally, don’t miss the events section, where you can find the registration details for the CHARISMA Raman School 2022 as well as other event announcements, including news of the NMBP-13 Projects’ Final Conference. We hope you enjoy reading this issue and find it useful and informative.