Background: Post-stroke motor function disability is a common complication in patients with stroke and a key contributor to impaired hand function after stroke: Cerebrovascular accident (CVA) is the second most frequent cause of death in the world. Nevertheless, most victims do survive and need treatment, and hand function is one that has to be dealt with in the rehabilitation process. Kinesio Taping (KT) is a bandaging method that can be applied along the muscle fibers to provide stimulation. Studies have shown its efficacy in providing afferent stimuli to weakened muscles, thus eliciting contraction with greater recruiting of motor units and inducing neuroplasticity. Objective: The purpose of this study was to investigate the effects of Kinesio taping on managing motor function of wrist motor performance in patients with sub-acute and chronic stroke. Method: An experimental comparative study design, 30 patients (mean age range40-66) with stroke and randomized 15patients in each group, Group A received conventional therapy and group B received kinesiotape with conventional therapy. Both groups were assessed in week o (before study) and week 5 (end of study) assessment measures were done using Fugl- Meyer scale and nine-hole peg test. Results: A total number of 30 patients were included in both the groups. 15 patients were put in Group A and B respectively. For Group A- treated with conventional therapy had undergone test on day 1(mean of pre-test readings) and after (mean of post-test reading) t=(p<0.0001). For Group B Kinesiotaping of wrist along with Conventional therapy. Total no patients (-M, -F with mean age) had undergone test on day 1(mean of pre-test) and after (mean of post-test) t=(p<0.0001). This study is to compare the Conventional therapy (mean=) and Conventional therapy with kinesiotaping of wrist (mean=) in chronic stroke Patients with two sample t-test for population mean with 5% level of significance. Conclusion: The effect of kinesiotaping along with conventional therapy is significantly better result as compare to conventional therapy on reducing spasticity and improving functional disability in patients with motor dysfunction.