Abstract : Background: Vital bleaching is most requested cosmetic dental procedure asked by patients who seek pleasing smile. Laser helps to reduce the stain and helps in teeth whitening. Aim: To investigate the effect of laser therapy induced by teeth bleaching. Methodology: A Literature review was performed using PubMed, Medline, PMC, Grey literature, Cochrane, Prospero, Wiley online library using MeSH term laser and teeth bleaching. Of a total 1658 appeared from various sources; all articles were screened and 14 were related to the research question and 5 were selected for the study. This review was reported according to PRISMA guidelines. Result: In the five studies of our systematic review shows that laser used in the case of teeth bleaching with higher concentration of hydrogen peroxide produced better result and comparatively lesser sensitivity than any other bleaching agents or lesser concentration of hydrogen peroxide. Conclusion: Clinical trials suggests that laser used in bleaching the tooth has better efficacy on tooth surface which resulted in lesser sensitivity and better tooth color, at the same time effectiveness of the treatment is same as that of the normal procedure.