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Conference object . 2022
License: CC BY
Data sources: Datacite
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ZENODO
Conference object . 2022
License: CC BY
Data sources: Datacite
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ZENODO
Other literature type . 2022
License: CC BY
Data sources: ZENODO
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Claim

Bis(monoacylglycerol) phosphate levels are elevated at baseline in carriers of pathogenic variants in LRRK2 and GBA1 and do not predict progression of PD in PPMI cohorts

descriptionPublicationkeyboard_double_arrow_right Conference object , Other literature type 31 Jul 2022 English Publisher:Zenodo
Authors: Kalpana M. Merchant; Tanya Simuni; Janel Fedler; Chelsea Caspell-Garcia; Michael Brumm; Kelly Nudelman; Elizabeth Tengstrandt; +10 Authors

doi: 10.5281/zenodo.7004951 , 10.5281/zenodo.7004952

Bis(monoacylglycerol) phosphate levels are elevated at baseline in carriers of pathogenic variants in LRRK2 and GBA1 and do not predict progression of PD in PPMI cohorts

Abstract

Urine Bis(monoacylglcerol) phosphate (BMP) has been identified as a biomarker that identifies carriers variants in the LRRK2 gene. The purpose of this study was to investigate BMP in patients with LRRK2-associated Parkinson’s disease in a longitudinal study. We found that BMP was elevated in patients with LRRK2 PD compared to sporadic PD. We did not identify phenotypic variation associated with LRRK2.

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Keywords

GBA1, LRRK2, Bis(monoacylglcerol) phosphate

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selected citations
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This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
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popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
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influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
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impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
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