Background: Iron deficiency Anaemia is one of the most common nutritional disorder world-wide, especially in India and other developing countries. In Ayurveda, Pandu is considered as a specific disease with its own Pathogenesis and treatment. In modern medicine, there is good treatment for Anaemia with considerable result but that is only for acute deficiencies Anaemias. No significant therapy is there for Chronic Anaemias which occur due to metabolic defects. Navayasachurna and Nisha Lauha both are herbomineralformulations which are effective in GIT disorders and chronic anemias. Materials& Methods: Total 80 Patients were registered of Iron Deficiency Anaemia. 15 patients were left the treatment before completion of therapy. Navayasachurna tablets were given in 33 patients of Group A and Nisha Lauha tablets were given in 32 patients of Group B. Result: Statistically highly significant result was foundinNavayasachurna Group A. Its also improved Hb, S. Iron and S. Ferritin level. So, it is suggested that Navayasachurna is helpful to improve appetite, digestion, clear the obstruction in channels, relieves constipation and increase Rasa- Rakta dhatu and improves Hb level. 21.21 % moderate improvement and 39.39% mild improvement was found in group A. Conclusion:Navayasachurna provided better improvement in Iron Deficiency Anaemia than Nisha Lauha.