This is the publicly accessible dataset reporting concentrations of thirteen analyzed minerals from hair using inductively coupled plasma mass spectrometry and relevant metadata from treponeme-associated hoof disease in Pacific Northwest elk. The data presented here were analyzed for the manuscript entitled "Associations between hair trace mineral concentrations and the occurrence of treponeme-associated hoof disease in elk (Cervus canadensis)." Please note that reported mineral concentrations are in their adjusted values and raw forms represented by the column name having ".Raw", (e.g., "Selenium" versus "Selenium.Raw"). Elk ecotype is represented by a four letter abbreviation for either Roosevelt (ROOS) or Rocky Mountain (ROMO). Unknown values for some variables (e.g., age class, county) are denoted with a "U."