In this paper, researcher present the research about blue brain and explained the concept and functioning about blue brain. The blue brain project is swiss brain research their aims to create a digital reconstruction of human brain. Blue brain is the project which was discovered by neurologist Henry Markram (Israeli) after his successful theory about blue brain project then he was moved to IBM and carried out their project with IBM. Generally blue brain is the name given to the world first virtual brain. That means the machine can function like Human's or Human brain. They attempt to create an artificial brain in which it can perform several functions just like humans like they can think, Sense, Response, take Decision and anything in memory. The blue brain project strategy is to convert a human brain into a virtual artificial brain. In blue brain it was concept related to neuroscience experiments and the literature through the database and analysis through digital reconstruction. It was first attempt to reverse-engineering.