To analyze the role of passive leg raising on cerebral oxygenation assessed with near-infrared spectroscopy (NIRS) in sepsis patients in the ICU RSUP H. Adam Malik using data from the mean value of cerebral oxygenation in sepsis patients and assessing the cerebral oxygenation difference before and after passive leg raising (PLR). Methods: It is a cross-sectional study conducted at H. Adam Malik Hospital, Medan from June 2021 until the sample is sufficient. Research subjects were taken by consecutive sampling technique, a total of 27 samples. Samples that met the inclusion criteria were monitored and recorded their hemodynamics (blood pressure, heart rate, mean arterial pressure) and rSO2using NIRS before PLR (T0) was performed. Furthermore, PLR was performed by raising the patient's legs 45° for 1 minute, and then monitoring and re-recording hemodynamics and rSO2was done (T1). Monitoring and re-recording were carried out 5 minutes after the PLR (T2) was performed with the NIRS pad still attached to the patient. Results: The results showed that there was a statistically significant difference between the right rSO2and the left rSO2before PLR and after 1-minute post-intervention with a p-value 0.05 showed that there was no statistically significant difference. Conclusion: There was a significant change in cerebral oxygenation after passive leg raising action, while at 5 minutes there was no significant change in cerebral oxygenation.