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The Multi-Component Reaction (MCRs) is a method in which three or more reactants are reacted in single vessel to form a complex cascade of molecule without isolation of intermediate. Here we have focused on various Multi-Component Reaction such as Strecker synthesis of amino acids, Hantzschsynthesis of dihydropyridines, Biginelli Reactions, Mannich reaction, Bucherer-Bergs synthesis and Kabachnik-Fields Reaction. Also discussed the concept map of above reactions which proceed through derivatization of carbonyl compound
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