Health has become a topic of increasing interest to investigators in the social and behavioral sciences over the past couple of decade. Health may be seen as a summation of functional capabilities (freedom from) unpleasant sensations or symptoms, and available reserves and resources, which can be drawn upon or mobilized to fend off threats to health. Frustration occurs when a person is unable to reach the desired goal on account of some barrier or other, or due to absence of desired and appropriate goals. Economic fluctuations can also thwart the achievement of desired goals and may create frustrations. The source of frustration may be internal also, resulting from his own incapability and inadequacy. Inability to achieve one’s goal may also lead to self-devaluation and inferiority. Frustration may lead to downfall and deviation because it wastes precious thinking ability and attention, which otherwise would have been used elsewhere in constructive and/or creative work. The purpose of this paper is to study the frustration and mental health of adolescents and relationship between frustration tolerance and mental health of adolescents.