Please cite the following paper when using this dataset: N. Thakur, “MonkeyPox2022Tweets: The first public Twitter dataset on the 2022 MonkeyPox outbreak,” Preprints, 2022, DOI: 10.20944/preprints202206.0172.v2 Abstract The world is currently facing an outbreak of the monkeypox virus, and confirmed cases have been reported from 28 countries. Following a recent “emergency meeting”, the World Health Organization just declared monkeypox a global health emergency. As a result, people from all over the world are using social media platforms, such as Twitter, for information seeking and sharing related to the outbreak, as well as for familiarizing themselves with the guidelines and protocols that are being recommended by various policy-making bodies to reduce the spread of the virus. This is resulting in the generation of tremendous amounts of Big Data related to such paradigms of social media behavior. Mining this Big Data and compiling it in the form of a dataset can serve a wide range of use-cases and applications such as analysis of public opinions, interests, views, perspectives, attitudes, and sentiment towards this outbreak. Therefore, this work presents MonkeyPox2022Tweets, an open-access dataset of Tweets related to the 2022 monkeypox outbreak that were posted on Twitter since the first detected case of this outbreak on May 7, 2022. The dataset is compliant with the privacy policy, developer agreement, and guidelines for content redistribution of Twitter, as well as with the FAIR principles (Findability, Accessibility, Interoperability, and Reusability) principles for scientific data management. Data Description The dataset consists of a total of 255,363 Tweet IDs of the same number of tweets about monkeypox that were posted on Twitter from 7th May 2022 to 23rd July 2022 (the most recent date at the time of dataset upload). The Tweet IDs are presented in 6 different .txt files based on the timelines of the associated tweets. The following provides the details of these dataset files. • Filename: TweetIDs_Part1.txt (No. of Tweet IDs: 13926, Date Range of the Tweet IDs: May 7, 2022 to May 21, 2022) • Filename: TweetIDs_Part2.txt (No. of Tweet IDs: 17705, Date Range of the Tweet IDs: May 21, 2022 to May 27, 2022) • Filename: TweetIDs_Part3.txt (No. of Tweet IDs: 17585, Date Range of the Tweet IDs: May 27, 2022 to June 5, 2022) • Filename: TweetIDs_Part4.txt (No. of Tweet IDs: 19718, Date Range of the Tweet IDs: June 5, 2022 to June 11, 2022) • Filename: TweetIDs_Part5.txt (No. of Tweet IDs: 47718, Date Range of the Tweet IDs: June 12, 2022 to June 30, 2022) • Filename: TweetIDs_Part6.txt (No. of Tweet IDs: 138711, Date Range of the Tweet IDs: July 1, 2022 to July 23, 2022) The dataset contains only Tweet IDs in compliance with the terms and conditions mentioned in the privacy policy, developer agreement, and guidelines for content redistribution of Twitter. The Tweet IDs need to be hydrated to be used.