Biological assays have been shifting towards miniaturization increasing lab work efficiency and enabling high-throughput. Microfluidics have shown intrinsic ability to manipulate very small volumes of fluids in a variety of integrated ways including sample processing, accurate control of fluids and delivery of results with a fast time. Huge potential of advanced automated point-of-care (POC) systems is expected. The founded association Microfluidics Innovation Hub (MIH) of the NextGenMicrofluidics OITB offers customers a single-entry point service catalog to a wide range of existing cutting-edge microfluidic technologies to accelerate the demonstration of scientific breakthroughs towards a working prototype and beyond into mass manufacturing. Here, we present preliminary results of the Safety & Sustainability assessment of next generation microfluidic devices for diagnostics applications.