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Abstract: Generally, cancer is a serious problem no matter what type of cancer, even though we have many types of medication, including vaccination. Most vaccines are created to prevent or boost immunity. However, the vaccine that this literature review mentioned was made to treat cancer. As the medical professionals wanted to treat the cancer patients precisely, a cancer vaccine was developed, not for prevention but as a cure by tricking the immune system. The vaccines have been developed using four melanoma antigens groups: overexpressed antigens, cancer-testis antigens, mutant oncogenes, and patient-specific mutated neoantigens. In addition, two technologies, Tumor antigens and Stimulation of anti-tumour immunity, have advanced based on the mechanism of cancer vaccines. Most importantly, the critical potential of cancer vaccine treatment for Melanoma has some clinical studies about the vaccinations that have been advanced and existed in much research, plus, it has been tested with humans. The history of melanoma skin cancer immunizations is extensive. It can stimulate immunological responses. An efficient vaccination platform is examined in this dynamic sector. This includes immunizations based on neoantigens and skin cancer virus inclusions. Keywords: Cancer vaccines, Melanoma antigens, Melanoma, Tumor antigens. Title: Cancer vaccine treatment for Melanoma Author: Supavee Piyapanpong International Journal of Healthcare Sciences ISSN 2348-5728 (Online) Vol. 10, Issue 1, April 2022 - September 2022 Page No: 144-152 Research Publish Journals Website: www.researchpublish.com Published Date: 14-July-2022 DOI: https://doi.org/10.5281/zenodo.6832997 Paper Download Link (Source) https://www.researchpublish.com/papers/cancer-vaccine-treatment-for-melanoma

International Journal of Healthcare Sciences, ISSN 2348-5728 (Online), Research Publish Journals, Website: www.researchpublish.com