Herbal extracts are used in dentistry for treatment of various dental disorders. The natural photochemical could offer an effective alternative to antibiotics and represent a promising approach to prevention and therapeutic strategies for various oral infections. The herbal remedies have an edge over conventional antibiotic treatment that suffer the limitation of low benefit to high risk as compared to herbal treatment that possess high benefit to low-risk ratio. The literature shows that several herbal formulations have the capacity to control the production of proinflammatory mediators, thereby managing many inflammatory processes. The use of such herbal anti-inflammatory formulations for a longer period of time was found to be safer than that of chemical anti-inflammatory drugs.Studies for assessment of safety and efficacy of herbal remedies are in its infancy. These herbal remedies are expected to widely use in future.