This dataset provides the output of eight model simulations with the global ocean biogeochemical model FESOM-REcoM necessary to reproduce the findings of Seifert et al. (2022). In addition to information on the mesh, the dataset contains 1) 5-year means of global phytoplankton biomass, chlorophyll, net primary production, growth rates, limitations, calcification, grazing rates, calcite concentrations, zooplankton biomass, export fluxes as well as CO2(aq), HCO3- and nutrient concentrations, and 2) a time series of global and North Atlantic coccolithophore biomass, temperature, and CO2(aq) concentrations from 1958 to 2018. File names refer to the Figures and Tables in the paper where the respective data are used. See “readme” for detailed information on the dataset and separate files.