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Drawing on information from SEC-MALLS, DIA-MS, XLMS, negative-stain EM, X-ray crystallography, NMR spectroscopy, secondary structure predictions, and homology models, we applied Bayesian integrative structure determination to investigate the molecular architecture of three NuRD sub-complexes: MTA1-HDAC1-RBBP4 (MHR), MTA1N-HDAC1-MBD3GATAD2CC (MHM), and MTA1-HDAC1-RBBP4-MBD3-GATAD2A (NuDe). The present dataset pertains to the results of this study.
Chemical crosslinks, Negative stain EM, PMI, Integrative Modeling Platform (IMP), Nucleosome Remodeling and Deacetylase Complex
Chemical crosslinks, Negative stain EM, PMI, Integrative Modeling Platform (IMP), Nucleosome Remodeling and Deacetylase Complex
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