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Molecular architecture of nucleosome remodeling and deacetylase sub-complexes by integrative structure determination

Authors: Arvindekar, Shreyas; Jackman, Matthew J.; Low, Jason K.K.; Landsberg, Michael J.; Mackay, Joel P.; Viswanath, Shruthi;

Molecular architecture of nucleosome remodeling and deacetylase sub-complexes by integrative structure determination

Abstract

Drawing on information from SEC-MALLS, DIA-MS, XLMS, negative-stain EM, X-ray crystallography, NMR spectroscopy, secondary structure predictions, and homology models, we applied Bayesian integrative structure determination to investigate the molecular architecture of three NuRD sub-complexes: MTA1-HDAC1-RBBP4 (MHR), MTA1N-HDAC1-MBD3GATAD2CC (MHM), and MTA1-HDAC1-RBBP4-MBD3-GATAD2A (NuDe). The present dataset pertains to the results of this study.

Keywords

Chemical crosslinks, Negative stain EM, PMI, Integrative Modeling Platform (IMP), Nucleosome Remodeling and Deacetylase Complex

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
views
OpenAIRE UsageCountsViews provided by UsageCounts
0
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8