Public health foresight is a systematic, participatory, and vision-building process that explores the future to anticipate trends and support present-day actions in the area of public health. Developed within the PHIRI (Population Health Information Research Infrastructure) project, this guide aims to support researchers in doing their own public health foresight studies. Facilitated by the project, this guide is the basis for those interested to develop their public health foresight study and exchange experiences with each other. This guide may also assist policy makers in understanding the foresight process and the need to include foresight in the policy cycle, to generate long-term benefits for society.