Complete androgen insensitivity syndrome or testicular feminization syndrome is the most common form of male pseudohermaphrodism, caused by a failure of androgen receptor binding. Patient with male genotype 46 XY, has a female morphotype with well developed external sexual organs. We report the case of two young patients aged 23 and 21 with a TF syndrome discovered during the exploration of primary amenorrhea. A bilateral orchiectomy was performed with institution of estrogen-progestogen hormone treatment.