Introduction: Infertility is a condition which affects the psychological as well as physiological well-being of a woman and her family. Among the causes of female infertility, the most common cause is considered to be the tubal factor.[1] In ayurveda, fallopian tubes are correlated to the artavavaha srotas and its block is compared with the sanga srotodushti of this srotas. Case Presentation: In this case report, a patient with primary infertility since 6 years was diagnosed with right tubal blockage. After undergoing sadyovirechana, a course of dashamoola ksheera niruha basti, yoni prakshalana with dashamoola kwatha and mahanarayan taila uttara basti was done for 3 consecutive days. During this duration, oral medicines were also prescribed – maharasnadi kwatha, pushpadhanwa rasa and ashokarishta. After a month, repeat HSG showed bilateral spillage. She underwent donor sperm IUI as her husband was diagnosed with azoospermia and later on conceived. Conclusion: Ayurvedic interventions like niruha basti, uttara basti and yoni prakshalana along with internal medicines were found effective in the management of infertility due to tubal blockage.