A series of 2-amino-4-benzyl- and 4-benzoyl-thiazoles along with their 2-acetamido-5-chloromercuri and 2-acetamido-5-bromo derivatives have been prepared with a view to studying their chemotherepeutic properties. 2-Amino-4-benzoyl- and-4-benzylthiazoles have been obtained by condensing 1-phenyl-3-bromo-1,2-propanediones and 1-chloro-3-phenylacetones respectively with thiourea. The acetamido derivatives of these thiazole bases, when treated with HgCl2 solution, give corresponding 5-chloromercuri derivatives which, have further been converted to 5-bromo derivatives by the action of bromine. Some of the compounds are found to be bac­teriostatic \(in\) \(vitro\) tests against \(E.\) \(coli\) and \(S\). \(aureus.\)