Neurofibromatosis (NF) is a group of genetic disorders that primarily affect neural tissues. NF type I also known as Von Recklinghausens diseaseis the most common type of NF, it accounts for about 90% of all cases, with a prevalence rate of one in 3,000 births. The disease is often characterized by complex and multicellular neurofibroma which may lead to different complications for an affected individual throughout life, so it is important to throw light on type I NF.