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Sulphonamidochlorophthaleins have been synthesised with a view to studying their pharmacological properties. Phenophthalein on nitration yields 3`,3'-dinitropherolphthalein which on chlorination, followed by reduction. provides 5',5"-dichloro-3',3'’-diaminophenolphthalein. The latter on condensation with Nacetylsulphanilyl chloroide (ASC) affords a product which on hydrolysis yields 5',5'’-dichloro-3',3'’-disulph. anilylamidophenolphthalein.
Organic compounds, Pharmacological properties, Alkaline solution
Organic compounds, Pharmacological properties, Alkaline solution
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