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Superficial myofibroblastoma of the lower female genital tract is a rare benign, recently recognized neoplasm that mostly affects the vulvovaginal area. In this paper we reported a case of 47years old lady who had 3-Normal vaginal deliveries , she had presented with complain of dysuria , difficult micturition lower abdominal pain, heaviness in the vagina and vaginal discharges. Vaginal examination showed a well demarcated , smooth mass measuring about 7cm x3cm. Transvaginal ultrasound was performed which showed a well -defined isoechoic solid lesion with heterogenous echo pattern which occupied the upper portion of the anterior vaginal wall. Magnetic resonance imaging showed a lesion described as a well defined mass at the level of anterior vaginal wall measuring 3.1APX4.5TVX3.3CC cm. The mass was removed per vaginal route , histopathologically, the tumor was characterized by nodular stromal spindle cell lesion, well defined and partly encapsulated with myxoid degeneration and prominent vascular network. No necrosis is seen .No significant mitotic activity indentified. The findings were consistent with superficail myofibroblastoma. Immunohistochemistry stain was carried out which was positive for CD34, Desmin , Vimentin and weakly positive for ER.
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