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Conference object . 2021
License: CC BY
Data sources: Datacite
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ZENODO
Other literature type . 2021
License: http://creativecommons.org/licenses/by/2.0/legalcode
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ZENODO
Conference object . 2021
License: CC BY
Data sources: Datacite
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Optimization of pre-analytical conditions for unbiased isolation of Circulating Tumour Cells

descriptionPublicationkeyboard_double_arrow_right Conference object , Other literature type 05 May 2021Publisher:ZenodoFunded by:EC | PERSIST
Authors: Pires, LR; Carneiro, A; Lopes, C; Pesqueira, T; Piairo, P; Dieguéz, L;

doi: 10.5281/zenodo.6477417 , 10.5281/zenodo.6477416

Optimization of pre-analytical conditions for unbiased isolation of Circulating Tumour Cells

Abstract

The detection of circulating tumor cells (CTCs) in the blood of cancer patients has been correlated with bad prognosis and therapy resistance. however, finding CTCs in peripheral blood is challenging due to their low number. we have developed the RUBYchipTM, a microfluidic device that isolates CTCs from whole blood of patients with outstanding capture efficiency (>70%). to bring CTCs to the clinical routine it is necessary to define pre-analytical parameters to comply with new IVD regulation and assure reproducible results across laboratories. In this publication, we investigate the effect of blood sample preservation and storage on CTC isolation efficiency using the RUBYchipTM.

https://inl.int/wp-content/uploads/2022/02/booklet-of-abstracts-1.pdf

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Keywords

Circulating Tumor cells, liquid biopsy, microfluidics

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popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
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This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
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