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Gut metabolites predict Clostridioides difficile recurrence

Authors: Dawkins, Jennifer J.; Allegretti, Jessica R.; Gibson, Travis E.; McClure, Emma; Delaney, Mary; Bry, Lynn; Gerber, Georg K.;

Gut metabolites predict Clostridioides difficile recurrence

Abstract

This repository contains: 1. Data used for analyses from: A) 16S rRNA gene amplicon analysis after paired-end Fastq files were truncated, filtered, denoised, and merged ["1-ASV_Counts.xlsx"] B) Untargeted metabolomics as provided by Metabolon ["2-UntargetedMetabolomics.xlsx"] C) Precision SCFA analysis ["3-PrecisionSCFA.xlsx"] D) Clincal demographic data of the study cohort ["Clinical Demographics.csv"] 2. Detailed results of univariate analyses in sub-folder "Univariate analysis results" for clinical data, untargeted metabolomics data, SCFAs, and ASVs 3. Detailed results of predictive analysis in subfolder "Predictive Analyses results", including per-fold performance results ("9-PredictiveResults.xlsx") and analysis of predictive features for ASVs ("10-ASVsPredictiveAnalysis.xlsx"), untargeted metabolites ("11-MetabsPredictiveAnalysis.xlsx"), targeted SCFAs ("12-SCFAPredictive Analysis.xlsx"), clinical data ("13-DemoPredictiveAnalysis.xlsx") and all data ("14-AllDataPredictiveAnalysis.xlsx") 4. Data for generating all figures and analyses in the publication ("GenFigure&AnalysesData")

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
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popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
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