Safety should be of concern to both the motorists and commuters. It is against this background that the ensuing paper considered predictors of effective safety strategies among taxi drivers in Akure south Local Government Area (LGA), Ondo state, Nigeria. A descriptive research design was adopted with a population of two hundred male respondents. The research data was collected through a self-developed structured and validated questionnaire tagged (PPESSTAD) registered taxi drivers in Akure south LGA, Ondo state, Nigeria. The simple frequency count and percentages were used to answer the research question while inferential statistics of chi-square (x2) was used to test the significance of each hypothesis at 0.05 alpha level. Five hypotheses were formulated and were all significant (p<0.05). The conclusion of the study was that effective drivers’ education, reckless driving, use of seat belt, vehicular inspection and obedience to road traffic rules and regulations are all predictors of effective safety strategies among taxi drivers in Akure south LGA, Ondo state, Nigeria. Based on the findings, recommendations that could enhance effective safety strategies among taxi drivers in Akure south LGA, Ondo state, Nigeria were suggested.