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(CS 12) Ocular Manifestations of Intracranial Meningioma: A Case Series

Authors: Wan Nur Ain Wan Adnan;

(CS 12) Ocular Manifestations of Intracranial Meningioma: A Case Series

Abstract

Introduction: Meningiomas are the most common primary brain tumors in adults, representing approximately a third of all intracranial neoplasm. Ocular presentations can be variable. Herein, we present variable ocular presentations in intracranial meningioma. Results : Patients involved are 2 females and 1 male with disease onset ranging between 39 to 57 years old. Each of the patient presented with different ocular complaint. The first patient presented with transient visual obscuration and symptoms of raised intracranial pressure, with ocular examination revealed papilledema. The second patient had bilateral gradual visual loss with evidence of bilateral optic atrophy. The third patient had diplopia with protrusion of the right eyeball, which the examination showed severe right eye non-axial proptosis with mass effect and a complex unilateral ophthalmoplegia. MRI showed location of tumor at the olfactory groove, suprasellar and greater wing of sphenoid. The first patient had a complete resolution of ocular symptoms and papilledema post-surgical intervention, while the other 2 patients had worsening symptoms and declining visual functions. They required multiple surgeries and radiation therapy due to aggressive tumour progression. Discussion/Conclusion : Intracranial meningioma may pose a significant ocular morbidity. While some patients may respond well to treatment, the disease can be progressive and highly aggressive, causing a treatment challenge.

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selected citations
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This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
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popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
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