Anthocyanins are flavonoid containing polyphenolic phytochemicals. They are widely present in plants and accounts for different color shades displayed by the plant organs. A broad range of health-revitalizing effects is attributed to anthocyanins, constituting a vital part of the human diet. They are also accountable for ameliorating the detrimental effects of various lifestyle diseases, including cancer, cardiovascular disorders, neurological disorders, etc. These beneficial impacts highly depend on the bioavailability of anthocyanins, governed by their absorption and metabolism in the human body. The primary goal of this review is to summarize the latest anthocyanin knowledge while focusing on the chemistry, pharmacokinetics, and various biological advantages with anti-cancer, neuroprotective, antidiabetic, antioxidant, cardiovascular protective, vision improvement, antiviral, and antimicrobial effects.