Processed data for the manuscript "" available on bioRxiv at "" Data is available for the following samples CD34+ Multiome data : 2 replicates T-cell depleted bone marrow Multiome data: 2 replicates The following counts and fragments files are available for each replicate <sample>_filtered_feature_bc_matrix.h5: Feature counts from CellRanger ARC <sample>_atac_fragments.tsv.gz: ATAC fragments file from Cellranger ARC <sample>_atac_fragments.tsv.gz.tbi: Index files for ATAC fragments file from Cellranger ARC The following scanpy anndata objects are also available cd34_multiome_rna.h5ad: Anndata object with normalized data, cell type annotations and clusters for the RNA modality of CD34+ hematopoietic stem and progenitor cells cd34_multiome_atac.h5ad: Anndata object with peak counts, cell type annotations and clusters for the ATAC modality of of CD34+ hematopoietic stem and progenitor cells. cd34_multiome_rna.h5ad: Anndata object with normalized data, cell type annotations and clusters for the RNA modality of T-cell depleted bone marrow dataset. bm_multiome_atac.h5ad: Anndata object with peak counts, cell type annotations and clusters for the ATAC modality of T-cell depleted bone marrow dataset.