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PATHOMORPHOLOGICAL FINDINGS IN DOGS WITH SPONTANEOUS HEARTWORM DISEASE

Authors: Radoslav Rafailov; Georgi Popov; Kostadin Kanchev; Vasil Manov;

PATHOMORPHOLOGICAL FINDINGS IN DOGS WITH SPONTANEOUS HEARTWORM DISEASE

Abstract

{"references": ["Atwell, R.B., R.H. Sutton, I.B. Buoro. (1986). Early pulmonary lesions caused by dead Dirofilaria immitis in dogs exposed to homologus antigens. The British Journal of experimental pathology, 67, 3, 395\u2013405", "Bancroft, J. D. & M. Gamble. (2002). Theory and practice of histological techniques 5th ed., Churchill Livingstone Publications, Edinburgh, UK", "Boreham, P. F. (2018). Dirofilariasis. CRC Press. Boca Raton, 99\u2013127", "Borisov, B., G. Marinov, P. Panayotov, N. Zlateva. (2017). Vector born diseases in dogs \u2013 Dirofi-lariosis and Anaplasmosis. A clinical study. Tradition and modernity in veterinary medicine, 2, 2, 59\u201366.", "Calvert C.A. & J. M. Losonsky. (1985). Occult heartworm-disease associated allergic pneumonitis. Journal of the American Veterinary Medical Association, 186, 10, 1097\u20131098.", "Carreton, E., Grandi, G., Morch\u00f3n, R., Sim\u00f3n, F., Passeri, B., Cantoni, A. M., Montoya-Alonso, J. A. (2012). Myocardial damage in dogs affected by heartworm disease (Dirofilaria immitis): im-munohistochemical study of cardiac myoglobin and troponin I in naturally infected dogs. Veterinary parasitology, 189, 4, 390\u2013393.", "Ceribasi, O. & S. Simsek. (2012). Histopathologic effects of Dirofilaria immitis microfilaria on in-ternal organs of dog confirming by PCR technique. Iranian journal of parasitology, 7, 2, 103.", "Dillon, A. R., Warner, A. E., Molina, R. M. (1995). Pulmonary parenchymal changes in dogs and cats after experimental transplantation of dead Dirofilaria immitis. In Proceedings of the heartworm symposium, Auburn, Alabama, 97\u2013101", "Grandi, G., Zivicnjak, T., Beck, R. (2007). Pathogenesis of Dirofilaria spp. infections. Dirofilaria immitis, Mappe Parassitologiche, 60\u201361.", "Grauer, G.F., C.A. Culham, A.J. Cooley, B.C. Poff, T.D. Oberley, M.S. Brownfield, R.B. Grieve. (1987). Clinicopathologic and histologic evaluation of Dirofilaria immitis-induced nephropathy in dogs. American Journal of Tropical Medicine and Hygiene, 37, 588\u2013596", "Iliev, P., Z. Kirkova, A. Ivanov, P. Prelezov, A. Tonev, I. Kalkanov. (2017). Retrospective analysis on helminthic and protozoan infections in dogs and cats in Bulgaria. Bulgarian Journal of Veterinary Medicine, 20, 1, 389\u2013393", "Kostadinov, \u041c. (2016). Dirofilariasis in dog. Veterinary practice, 3, 26\u201333.", "Kramer, L., Grandi, G., Passeri, B., Gianelli, P., Genchi, M., Dzimianski, M. T., McCall, J. W. (2011). Evaluation of lung pathology in Dirofilaria immitis-experimentally infected dogs treated with doxycycline or a combination of doxycycline and ivermectin before administration of me-larsomine dihydrochloride. Veterinary parasitology, 176, 4, 357\u2013360", "Nakagaki, K., M. Hayasaki, I. Ohishi. (1990). Histopathological and immunopathological evalua-tion of filarial glomerulonephritis in Dirofilaria immitis infected dogs. The Japanese Journal of Ex-perimental Medicine, 60, 4, 179\u2013186.", "Paes-de-Almeida, E. C., Ferreira, A. M. R., Labarthe, N. V., Caldas, M. L. R., McCall, J. W. (2003). Kidney ultrastructural lesions in dogs experimentally infected with Dirofilaria immitis (Leidy, 1856). Veterinary parasitology, 113, 2, 157\u2013168.", "Panayotova-Penchev\u0430, M., R. L. Mirchev, A. P. Trifonova. (2016). Dirofilaria immitis infection in carnivores from Bulgaria: 2012-2013 update. Bulgarian Journal of Veterinary Medicine, 19, 2, 153\u2013162.", "Pasca, S. A., Acatrinei, D., Oprean, O. Z., Lazar, M. (2012). Vascular, hepatic and renal lesions by Dirofilaria immitis invasion in dogs. Arquivo Brasileiro de Medicina Veterin\u00e1ria e Zootecnia, 64, 4, 841\u2013846", "Radev, V., N. Lalkovski, P. Zhelyazkov, T. Kostova, P. Sabev, N. Nedelchev, R. Vassileva. (2016). Prevalence of gastrointestinal parasites and Dirofilaria spp. in stray dogs from some regions in Bulgaria. Bulgarian Journal of Veterinary Medicine, 19, 1, 57\u201362.", "Rafailov, R. (2020). Prevalence of Dirofilaria immitis in dogs in Bulgaria. Tradition and modernity in veterinary medicine, 5, 9, 57\u201364.", "Ranjbar-Bahadori, S., M. Mohri, J.A. Helan, K. Jamshidi, M. Kashefinejad. (2010). Clinico-patho-logic evaluation of the canine Heartworm infestation. Research Journal of Parasitology, 5, 90\u201398.", "Stoev, S., I. Dinev, V. Manov, R. Simeonov, N. Grozeva. (2016). Mannual for practical lessons in veterinary necropsy equipment and rendering. Contrast, Stara Zagora, 79\u201383.", "Zachary J. F. (2017). Pathologic basis of veterinary disease. Elsevier Health Sciences, Urbana, 6, 609\u2013615"]}

Study reveals the pathomorphological findings of 6 dogs, 3 males and 3 females, diagnosed with Heartworm disease. By necropsies were found a total number of 144 adult stages (74 male and 70 female) of the nematode Dirofilaria immitis, located in a. pulmonalis, right ventricle and atrium and sulcus vena cavae. The gross pathology shows right-sided enlargement of the heart, dilated pulmonary arteries, and single petechial hemorrhages in the lungs. Histopathologically, degenerative changes in the pulmonary arteries, thickening of the pulmonary valves, interstitial reactions in the lungs and protein precipitates in the kidneys were found

Country
Bulgaria
Keywords

Dirofilaria immitis, dogs, gross and histopathological findings., Dirofilaria immitis, dogs, gross and histopathological findings, gross and histopathological findings, Dirofilaria immitis,, dogs,

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popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
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This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
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