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Dynamics of the tumor immune microenvironment during ne-oadjuvant chemotherapy of high-grade serous ovarian cancer

descriptionPublicationkeyboard_double_arrow_right Article 18 Mar 2022Publisher:Zenodo
Authors: Lee, Yong Jae;

doi: 10.5281/zenodo.6367522 , 10.5281/zenodo.6511709 , 10.5281/zenodo.6367521

Dynamics of the tumor immune microenvironment during ne-oadjuvant chemotherapy of high-grade serous ovarian cancer

Abstract

Supplemental Figure S1: Comparison of immune cell fraction between pre- and post-NAC tumor samples by CIBERSORT. Supplemental Figure S2: Forest plot showing the association between immune cell fractions, platinum sensitivity, and progression-free survival rate at 12 months. (a) Platinum sensitivity. Platinum sensitivity was defined as recurrence 6 months after platinum-based chemotherapy, while platinum resistance was defined as recurrence within 6 months from platinum-based chemotherapy. (b) Progression-free survival rate at 12 months. Supplemental Figure S3: Gene set enrichment analysis of differentially expressed genes in pre- and post-NAC samples. (a) JAK/STAT signaling pathway. (b) Co-stimulation by the CD28 family. Supplemental Table S1. Gene content in the TruSight Tumor 170 panel

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This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
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