Aim: To evaluate the best result in stroke assessment using various MRI sequences. Background: Stroke is considered as a major disorder in todays world. MRI is used for diagnosis of CVA patients. MRI can identify accurately hemorrhagic and ischemic stroke patients in the acute, subacute and chronic stage. Hypothesis: Which sequence give detailed study of CVA in MRI? Data sources: As a literature review project, the methods and materials which supports this project are based on previous publications of the literature, indexed on Pubmed-Medline, Medscape, AMED,CINAHL and SCIRUS from 2000-2010. A computerized database search was performed using the Oxfords University OxLIP + interface and each of the article and studies that met the criteria for that project was evaluated. Even the data is collected from the MGM Hospital of Navi Mumbai. Result: In my study the findings were Diffusion MRI sequence was more sensitive for around 80% and FLAIR sequence was also specific (specificity near about 60%) for detection of early(Hyperacute to Acute) stroke cases. T2 axial sequences were more helpful in chronic stroke cases which is about 40% in specification along with GRE. FLAIR sequence was more helpful. Conclusion: MRI diffusion sequence is more specific and sensitive in Hyper acute and Acute stroke cases and FLAIR is helpful in Chronic stroke cases.