The purpose of this study is to compare the phytochemical evaluation of Dendropthoe falcata (l.f) ettingsh (Loranthaceae) grown on Azardirachta indica and Nerium oleander as host plants. In the Azadirachta indica, the preliminary phytochemical test revealed the presence of alkaloids, reducing sugar, glycosides, flavonoids, tannins and saponins, while in the Nerium oleander, the preliminary phytochemical test revealed the presence of alkaloids, reducing sugar, glycosides, flavonids, tannis, saponin, phlobatannins and phytosterol. The preliminary phytochemical screening of the two host plant, the study revealed that Nerium oleander having better quality phytoconstituents than Azadirchta indica and this attributes to its traditional medicinal use. Keywords: Dendropthoe falcata, Azardirachta indica, Nerium oleander, alkaloids, flavonoids, saponins, phlobatannins.