This study proposes Buddhism researcher may apply case study method in combing business management and fundamental Buddhist concepts, such as: five precepts and ten virtues, three good four giving, dependent origin, middle way, twelve karma, three seals, four noble truths, six degrees Four photographs, to enlarge the scope of Buddhism research. It is our aspiration to utilize case studies and literature research to establish the "Manual for Entrepreneurs of Human Buddhism" in order to give entrepreneurs Dharma guidance. We also propose a fourth type entrepreneur in the future: Entrepreneurs of Humanistic Buddhism. Their core value is social responsibility and The Three Good: (1) doing good deeds in the body, (2) speaking good words, and (3) having good thoughts in the heart.