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Article . 1990
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Article . 1990
License: CC BY
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Article . 1990
License: CC BY
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Conductance Behaviour of some associated Hydrochlorides of Medicinal Interest in Aqueous Solution at 298 K

Authors: S. C. DUTTA; S. DAS; S. C. LAHIRI;

Conductance Behaviour of some associated Hydrochlorides of Medicinal Interest in Aqueous Solution at 298 K

Abstract

Department of Chemistry, University of Kalyani, Kalyani-741 235 Manuscript received 12 April 1989, revised 19 September 1989, accepted 6 February 1990 The conductance studies of hydrochlorides of well-known druge (like pseudoephedrine, isoxsuprine, metoclopramide, pentazocine, propranalol, dicyclomine and �����-phenylpropanolamine) in aqueous solutions have been made. The analysis of the results using Shedlovsky's equation indicates that the compounds are associated in aqueous solutions. Improved values of the association constants K��� and ��o have been determined using Fuoss equation. The ��o values of the cations compare very well with those fortetraalkylammonium ions and it is expected that they undergo hydrophobicinteractions in aqueous solutions.

Keywords

Hydrochlorides, Metoclopramide, Phenylpropanolamine

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