
Downsampled version of the melanoma dataset originally published by Ho et al (1). The dataset is composed by cells from the 451Lu cell line. There are two samples available: Name Description R1/R2 451LU Parental cell line 2500K_451LU_L003_R*_001.fastq.gz 451LUBR3 Vemurafenib-resistant sample treated with targeted BRAF inhibitors 500K_451LUBR3_L004_R*_001.fastq.gz (1) Ho YJ, Anaparthy N, Molik D, et al. Single-cell RNA-seq analysis identifies markers of resistance to targeted BRAF inhibitors in melanoma cell populations. Genome Res. 2018;28(9):1353-1363. doi:10.1101/gr.234062.117
{"references": ["Ho YJ, Anaparthy N, Molik D, et al. Single-cell RNA-seq analysis identifies markers of resistance to targeted BRAF inhibitors in melanoma cell populations. Genome Res. 2018;28(9):1353-1363. doi:10.1101/gr.234062.117", "Garc\u00eda-Jimeno, L., Fustero-Torre, C., Jim\u00e9nez-Santos, M. J., G\u00f3mez-L\u00f3pez, G., Di Domenico, T., & Al-Shahrour, F. (2022). bollito: a flexible pipeline for comprehensive single-cell RNA-seq analyses. Bioinformatics, 38(4), 1155-1156."]}
The original single-cell data can be accessed through the Gene Expression Omnibus (GEO), accession number GSE108394.
single-cell RNA-seq, snakemake pipeline, bollito
single-cell RNA-seq, snakemake pipeline, bollito
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