Downloads provided by UsageCounts
This link consists of 10 anonymized non-small cell lung cancer (NSCLC) field of Views (FoVs) to test Mistic. Mistic Understanding the complex ecology of a tumor tissue and the spatio-temporal relationships between its cellular and microenvironment components is becoming a key component of translational research, especially in immune-oncology. The generation and analysis of multiplexed images from patient samples is of paramount importance to facilitate this understanding. In this work, we present Mistic, an open-source multiplexed image t-SNE viewer that enables the simultaneous viewing of multiple 2D images rendered using multiple layout options to provide an overall visual preview of the entire dataset. In particular, the positions of the images can be taken from t-SNE or UMAP coordinates. This grouped view of all the images further aids an exploratory understanding of the specific expression pattern of a given biomarker or collection of biomarkers across all images, helps to identify images expressing a particular phenotype or to select images for subsequent downstream analysis. Currently there is no freely available tool to generate such image t-SNEs. Links Mistic code Mistic documentation Paper
t-SNE viewer, CODEX, Endometrial cancer, Multiplexed images, UMAP viewer, data exploration, Immune landscape, Mistic, PerkinElmer Vectra, Immunotherapy, Lung cancer, t-CyCIF
t-SNE viewer, CODEX, Endometrial cancer, Multiplexed images, UMAP viewer, data exploration, Immune landscape, Mistic, PerkinElmer Vectra, Immunotherapy, Lung cancer, t-CyCIF
| selected citations These citations are derived from selected sources. This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically). | 0 | |
| popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network. | Average | |
| influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically). | Average | |
| impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network. | Average |
| views | 59 | |
| downloads | 43 |

Views provided by UsageCounts
Downloads provided by UsageCounts